Methylene blue is a synthetic chemical compound that has a vibrant blue colour. It was first synthesised in the 19th century and was initially used as a dye and an antimalarial drug. However, in recent years, researchers have uncovered its ability to boost brain function and protect against age-related cognitive decline.

It works by optimising mitochondrial function, the energy powerhouses of your cells, leading to improved brain function and overall cognitive well-being.

Methylene blue offers a range of potential benefits, from boosting brainpower to supporting overall health. Here's a breakdown:

Cognitive Enhancement

Improved Focus and Concentration: Methylene blue can help you hone your attention, making it easier to stay on task and avoid distractions.

Enhanced Memory: Experience sharper recall and improved memory retention, whether it's remembering names, dates, or crucial information.

Increased Mental Energy: Say goodbye to brain fog and hello to sustained mental energy throughout the day.

Mood and Well-being

Elevated Mood: Methylene blue may help promote a more positive mood and reduce feelings of stress and anxiety.

Improved Sleep: Some individuals find that methylene blue can contribute to more restful sleep.

Neuroprotection

Antioxidant Effects: Methylene blue acts as an antioxidant, protecting brain cells from damage caused by free radicals.

Potential for Age-Related Cognitive Decline: Research suggests that methylene blue may play a role in protecting against age-related cognitive decline and neurodegenerative diseases.

Other Potential Benefits

Anti-malarial Properties: Methylene blue has a history of use in treating malaria.

Wound Healing: Methylene blue may aid in wound healing due to its antimicrobial properties.

Methemoglobinemia Treatment: It's used in the treatment of methemoglobinemia, a rare blood disorder.

All of Boost⁺ products are manufactured and packaged in China, developed in Australia, and third-party tested by laboratories in the USA. 

In fact, all methylene blue that you see on the market is produced in China or India. Even if they say 'Made in Australia', they are only referring to the end packaging of the product, and not the manufacturing of the ingredients. Currently, the TGA does not permit the manufacturing and sale of methylene blue from within Australia, so any company claiming to have Australia-made products is doing so illegally. The TGA does however allow Australian consumers to purchase and consumer these supplements from overseas.

For this reason, all of Boost⁺'s supply chain, including our shipping warehouse, is based in Hong Kong. We ship every order daily with Australia Post, arriving in 5-7 days with express options available.

Methylene blue is synthetic. It's a manufactured chemical compound, first synthesised in a lab in 1876.

Yes, yes and yes. Our methylene blue is vegan, GMO-free, and does not contain anything other than pure methylene blue.

Yes. We test every batch of methylene blue, and all Boost⁺ products for purity, before they're released to customers. We also share the certificate of analysis on every product page. All Boost⁺ methylene blue demonstrates purity in excess of 99%, and is free of heavy metals.

It has also been stability tested through a 30 day test to ensure our product remain stable even in 40C temperatures. We didn't find any significant degradation in the product.

Generally at recommended dosages, people do not face side effects with methylene blue.While it is considered safe for most people, there are some potential side effects that you should be aware of.

Potential Side Effects:

Blue Urine and Stool: This is a harmless and very common side effect. Don't be alarmed if your urine or stool turns a bluish-green color!

Headaches: Some people may experience headaches, especially when first starting to take methylene blue.

Nausea and Upset Stomach: Gastrointestinal discomfort can occur in some individuals.

Less Common Side Effects:

Anxiety or Restlessness: While some people report reduced anxiety, others might experience the opposite effect.

Insomnia: Methylene blue can interfere with sleep for some individuals, especially if taken later in the day.

High Blood Pressure: In some cases, methylene blue can elevate blood pressure.

Allergic Reactions: Although rare, allergic reactions can occur. Seek medical attention if you experience symptoms like hives, difficulty breathing, or swelling.

Serious Side Effects (Rare):

Serotonin Syndrome: This is a rare but serious condition that can occur when methylene blue interacts with certain medications that increase serotonin levels. Symptoms include confusion, agitation, rapid heartbeat, and fever. Seek immediate medical attention if you suspect serotonin syndrome.

Hemolytic Anemia: In rare cases, methylene blue can cause hemolytic anemia, a condition where red blood cells are destroyed faster than they can be produced.

Important Considerations:

Dosage: Side effects are more likely to occur at higher doses.

Individual Sensitivity: People react differently to substances. What causes side effects in one person might not in another.

Drug Interactions: Methylene blue can interact with certain medications, such as antidepressants and MAO inhibitors. Always consult with your doctor before taking methylene blue, especially if you are on other medications.

If you experience any concerning side effects, stop taking methylene blue and contact your healthcare provider.

Everyone metabolises methylene blue differently, so some people may notice effects more quickly than others. 

Typically though, below is a good timeline of benefits you may experience:

Day 1: The Initial Boost

Within the first few hours: Many people report feeling a noticeable increase in mental clarity and focus shortly after taking their first dose. It's like a gentle "awakening" of your cognitive abilities.

Throughout the day: You might find it easier to concentrate on tasks, absorb information, and stay mentally sharp. That afternoon slump? Methylene blue might just help you power through it.

Day 2-3: Sustained Energy and Mood

Consistent energy levels: You'll likely notice a more sustained level of mental energy throughout the day. Say goodbye to those mid-day crashes and hello to consistent focus and productivity.

Mood lift: Many people report feeling a subtle mood boost, with reduced feelings of stress and anxiety. You might find yourself approaching challenges with a greater sense of calm and clarity.

Day 4-7: Memory and Creativity Enhancements

Sharper memory: You might start to notice improvements in your memory recall. Remembering names, dates, and details becomes more effortless.

Creative spark: Some individuals report feeling more creative and innovative during this period. Ideas flow more freely, and problem-solving feels more intuitive.

Beyond the First Week: Long-Term Benefits

Continued cognitive enhancement: With consistent use, the cognitive benefits of methylene blue can become even more pronounced. You might experience a sustained improvement in focus, memory, and mental clarity.

Neuroprotection: The long-term antioxidant and neuroprotective effects of methylene blue can contribute to overall brain health and resilience.

Important Notes:

Individual variation: Everyone's experience with methylene blue is unique. Some people might notice effects immediately, while others might take a few days or weeks to see significant changes.

Dosage and consistency: The timing of results can also depend on the dosage and how consistently you take methylene blue.

Lifestyle factors: A healthy lifestyle, including proper nutrition, sleep, and stress management, can complement the effects of methylene blue and optimize your cognitive function.

If you have any concerns or questions about your experience with methylene blue, don't hesitate to reach out to your healthcare provider. They can provide personalized guidance and support on your journey to cognitive enhancement.

Methylene blue has a slightly bitter and metallic taste. Some people also describe it as having a slightly salty or chemical taste.

The intensity of the taste can vary depending on the concentration and formulation of the methylene blue.

No, not necessarily. However, methylene blue will temporarily stain anything it touches and some don’t want a blue mouth for their day. You can mix MB with water or even a juice (OJ works best to reduce the blue color) and still get the same benefits! Some of our Boosters love having fun with the blue colour it leaves on your tongue. Snap a pic and tag us!

While methylene blue isn't currently a proven treatment for Alzheimer's, it shows promise and is being actively studied. Here's what we know so far:

How Methylene Blue Might Help

Mitochondrial Support: Alzheimer's is linked to mitochondrial dysfunction in brain cells. Methylene blue can boost mitochondrial function, potentially improving energy production and protecting cells.

Tau Tangles: A hallmark of Alzheimer's is the buildup of "tau tangles" in the brain. Methylene blue has been shown to inhibit the formation of these tangles.

Amyloid Plaques: Another characteristic of Alzheimer's is the accumulation of amyloid plaques. While the evidence is less clear-cut, some studies suggest methylene blue might help reduce these plaques.

Antioxidant Effects: Methylene blue can act as an antioxidant, protecting brain cells from damage caused by oxidative stress, which is implicated in Alzheimer's.

Research and Clinical Trials

Early Studies: Several small studies have shown that methylene blue can improve cognitive function in people with mild to moderate Alzheimer's.

Larger Trials: Larger clinical trials are underway to further investigate the effectiveness and safety of methylene blue for Alzheimer's.

Combination Therapies: Researchers are also exploring the potential of methylene blue in combination with other treatments for Alzheimer's.

While methylene blue isn't a traditional antidepressant, there's growing evidence that it has a role to play in alleviating depression symptoms for some people.

Here's how it might work:

Boosting Brain Energy: Depression is often linked to low energy levels in certain brain regions. Methylene blue can enhance mitochondrial function, increasing energy production in brain cells. This could potentially help improve mood and cognitive function.

Neurotransmitter Balance: Methylene blue can affect the levels of certain neurotransmitters in the brain, such as dopamine, serotonin, and norepinephrine. These neurotransmitters play a key role in mood regulation.

Antioxidant and Anti-inflammatory Effects: Depression is sometimes associated with oxidative stress and inflammation in the brain. Methylene blue has antioxidant and anti-inflammatory properties that might help address these factors.

What the Research Says:

Small Studies: Some small studies have shown promising results, suggesting that methylene blue can improve mood and reduce depression symptoms in certain individuals.

More Research Needed: Larger, more rigorous studies are needed to confirm these findings and determine the optimal dosage and treatment protocols.

While methylene blue isn't a typical anxiety medication, some evidence suggests it could play a supporting role in managing anxiety for some individuals.

Here's how it might work:

Brain Energy and Mitochondrial Function: Anxiety can sometimes be linked to imbalances in brain activity and energy metabolism. Methylene blue can enhance mitochondrial function, potentially improving energy production in brain cells and promoting more balanced brain activity.

Neurotransmitter Modulation: Methylene blue can influence the levels of certain neurotransmitters in the brain, such as serotonin and norepinephrine, which are involved in mood regulation and anxiety responses.

Oxidative Stress Reduction: Anxiety can be associated with increased oxidative stress in the brain. Methylene blue has antioxidant properties that might help reduce this stress.

What the Research Suggests:

Limited Evidence: The research on methylene blue for anxiety is still quite limited, with mostly small studies or preclinical research.

Potential Benefits: Some studies have shown that methylene blue can reduce anxiety-related behaviours in animals and may have some anxiolytic effects in humans.

Methylene blue has a complex relationship with sleep, and its effects can vary from person to person.

Here's what we know:

Some people find that methylene blue can actually improve their sleep quality. This might be due to its effects on:

Mitochondrial function:
Methylene blue can influence neurotransmitters like serotonin, which play a role in sleep regulation.

Some evidence suggests that methylene blue might help synchronise the body's natural sleep-wake cycle.

On the other hand, some people find that methylene blue can interfere with their sleep. This could be due to:

Stimulating effects:
Anxiety or restlessness: In some cases, methylene blue can increase anxiety or restlessness, which can disrupt sleep.

Factors Influencing Sleep Effects:

Dosage: Lower doses of methylene blue are less likely to interfere with sleep.

Timing: Taking methylene blue earlier in the day can help minimize any potential sleep disturbances.

Individual sensitivity: People react differently to substances, so what works for one person might not work for another.

Okay, let's dive into the fascinating world of methylene blue and its impact on those tiny but mighty powerhouses of our cells - the mitochondria!

Mitochondria: The Cellular Power Plants

Think of mitochondria as the energy factories within our cells. They're responsible for producing ATP (adenosine triphosphate), the primary energy currency that fuels all cellular processes. When our mitochondria are functioning optimally, our cells have the energy they need to thrive, and our bodies and minds perform at their best.

Methylene Blue: A Mitochondrial Booster

Methylene blue has a unique ability to enhance mitochondrial function. It acts like a "supercharger" for these cellular power plants, optimizing their energy production and improving overall cellular efficiency.

Here's how it works:

Methylene blue plays a crucial role in the electron transport chain, a series of protein complexes within the mitochondria that generate ATP. It acts as an electron donor and acceptor, facilitating the flow of electrons and enhancing energy production.

This is the process by which ATP is generated in the mitochondria. Methylene blue can improve the efficiency of oxidative phosphorylation, leading to increased ATP production.

Methylene blue has antioxidant properties that can help protect mitochondria from damage caused by free radicals. This can help maintain their optimal function and prevent cellular ageing.

The Benefits of Enhanced Mitochondrial Function

Improved mitochondrial function can have a wide range of positive effects on our health and well-being, including:

Increased energy levels: Feel more energized and alert throughout the day.

Enhanced cognitive function: Experience improved focus, memory, and mental clarity.

Improved mood: Promote a more positive mood and reduce feelings of stress and anxiety.

Neuroprotection: Protect brain cells from damage and age-related decline.

Anti-ageing effects: Slow down the aging process and promote cellular longevity.

You should NOT be consuming methylene blue if you are currently on antidepressants or MAO inhibitors.

Long-term side effects are rare when consumption is responsibly managed.

We recommend taking no more than the recommended dosage of 5mg per day.

We also recommended cycling methylene blue.

Cycling methylene blue is a strategy some people use to potentially minimise the risk of long-term side effects and maintain the effectiveness of the compound. Here's a common approach:

Typical Cycling Schedule

"On" Cycle: Take methylene blue daily for a certain period, typically 5 days a week.

"Off" Cycle: Take a break from methylene blue for 2 days a week.

Some people prefer longer cycles such as 2 weeks on and 1 week off.

Benefits of Cycling

Reduced Side Effects: Taking breaks may help prevent the buildup of methylene blue in the body and reduce the risk of potential long-term side effects.

Maintaining Effectiveness: Cycling could help prevent your body from adapting to methylene blue, potentially maintaining its effectiveness over time.

Important Considerations

Individual Needs: The optimal cycling schedule can vary depending on individual factors like dosage, sensitivity, and health conditions.

Consult Your Doctor: It's always best to discuss cycling strategies with your doctor to ensure they align with your individual needs and health goals.

Side effects are uncommon, however, here are some potential long-term effects to be aware of:

Neurotoxicity: Some studies have suggested that very high doses or prolonged use of methylene blue might have neurotoxic effects, potentially damaging brain cells. However, this is mainly a concern at doses far exceeding those typically used for cognitive enhancement.

Serotonin Syndrome Risk: If you're taking methylene blue alongside other medications that increase serotonin levels (like antidepressants or MAO inhibitors), there's a potential risk of serotonin syndrome, even with long-term use. This is a serious condition that requires immediate medical attention.

Drug Interactions: Methylene blue can interact with various medications. If you're taking any medications regularly, it's crucial to talk to your doctor before using methylene blue to avoid potential long-term interactions.

It's generally not recommended because mixing methylene blue with other ingredients in a smoothie could affect its absorption in the body.

It's best to avoid mixing methylene blue into food or hot drinks as the heat from hot drinks and food could potentially degrade methylene blue, reducing its effectiveness.

To unlock the full cognitive benefits of methylene blue, we recommend a daily dosage of 5mg - 15mg. 90% of our people report 5mg to be their go to dose. That's just 20 drops from our bottle. We recommend starting with 5-10 drops first. Less is more with methylene blue.

First and foremost, it's always best to consult your doctor before commencing any new supplement whilst breastfeeding and it's always best to err on the side of caution. For that reason, we recommend not taking methylene blue whilst pregnant or breastfeeding.

Most notice an increase in energy, focus, and mood almost immediately after trying. A sense of well-being is an easy way to explain the feeling! If you don’t get this feeling right away that is okay as well! Some people start to notice effects after a few days or when they increase the amount of drops.

Methylene Blue is very antipathogenic! When you introduce it into your system at first you can have what is known as Herxheimer effect. This is due to MB killing off any pathogens in the body. If you suspect you’re having a Herxheimer reaction, stop taking MB for a few days, drink plenty of fluids, and try a smaller dose!

Yes! This is completely normal. It will vary from day to day depending on the dose, hydration levels, and micronutrients in your food intake.

No and it actually speeds up the effects of a fast! Mitophagy is sped up by combining MB and fasting.